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Selected Pharmaceuticals in Late Stage U.S. and E.U. Development or Registration as of July 21, 2021

Immunology

STELARA (ustekinumab)

Pediatric Crohn's Disease
Phase III US
Phase III EU

STELARA (ustekinumab)

Pediatric Ulcerative Colitis
Phase III US
Phase III EU

TREMFYA (guselkumab)

Psoriatic Arthritis Structural Damage
Phase III US

Infectious Diseases and Vaccines

VAC52416

Multivalent ExPEC Vaccine
Phase III US
Phase III EU

Oncology

RIS/gemcitabine plus cetrelimab

Muscle non invasive bladder cancer
Phase II US
Phase II EU
This information is accurate as of the date hereof to the best of the Company's knowledge. Johnson & Johnson assumes no obligation to update this information. (2) aprocitentan developed in collaboration with Idorsia; (3) XARELTO co-developed with Bayer HealthCare; (5) DARZALEX licensed from Genmab A/S; (6) IMBRUVICA developed in collaboration with Pharmacyclics, LLC, an AbbVie company; (7) BALVERSA discovered in collaboration with Astex Pharmaceuticals, Inc.; (8) Niraparib licensed from Tesaro; (9) BCMA CAR-T licensed from Legend Biotech; (10) Monovalent Ebola Vaccine developed in collaboration with Bavarian Nordic A/S, and MVA-BN-Filo® is licensed-in from Bavarian Nordic A/S; (11) DUOBODY platform licensed from Genmab relates to several bispecific antibody programs (Amivantamab, Teclistamab , Talquetamab);
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