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Pharmaceutical Pipeline

Download Report
= Achieved

Pharmaceutical Pipeline – Key Events in 2021*

POTENTIAL APPROVALS US/EU

CABENUVA (rilpivrine long acting)

HIV
US

ciltacabtagene autoleucel (BCMA CAR-T)

Relapsed refractory Multiple Myeloma
US

DARZALEX (daratumumab)

Amyloidosis (ANDROMEDA)
US
EU

DARZALEX (daratumumab)

Relapsed Refractory Multiple Myeloma w/PomDex
US
EU

INVEGA HAFYERA (PP6M)

Schizophrenia
US

PONVORY (ponesimod)

Relapsing forms of multiple sclerosis
US
EU

RYBREVANT (amivantamab)

Non Small Cell Lung Cancer
US

SPRAVATO (esketamine nasal spray)

Major Depressive Disorder in a Psychiatric Emergency
EU

UPTRAVI IV (selexipag)

Pulmonary arterial hypertension
US

VAC31518

Janssen COVID-19 Vaccine
EUA US
cMAA EU

XARELTO (rivaroxaban)

Infrainguinal revascular PAD
US

XARELTO (rivaroxaban)

Pediatric VTE/CHD (Fontan)
US

PLANNED SUBMISSIONS US/EU

ciltacabtagene autoleucel (BCMA CAR-T)

Relapsed refractory Multiple Myeloma
Submission Complete US
EU

IMBRUVICA (ibrutinib)

Frontline Chronic Lymphocytic Leukemia (I + V fixed duration) (GLOW)
US
EU

RYBREVANT (amivantamab)

Non Small Cell Lung Cancer
EU

VAC31518

Janssen COVID-19 Vaccine
EUA US
cMAA EU

XARELTO (rivaroxaban)

Pediatric VTE/CHD (Fontan)
US

POTENTIAL CLINICAL DATA PRESENTATIONS

Phase II

ciltacabtagene autoleucel (BCMA CAR-T)

Multiple Myeloma (CARTITUDE-1 Longer term follow-up)

milvexian (factor Xla)

Total Knee Replacement (AXIOMATIC-TKR)

RYBREVANT (amivantamab)

2L NSCLC (CHRYSALIS)
Phase III

DARZALEX (daratumumab)

Multiple Myeloma (MAIA) Overall Survival Benefit

ERLEADA (apalutamide)

Metastatic castrate sensitive prostate cancer- Final Analysis (TITAN)

IMBRUVICA (ibrutinib)

Frontline chronic lymphocytic leukemia (I+V fixed duration) (GLOW)

INVEGA HAFYERA (PP6M)

Schizophrenia (ROUTE 6)

STELARA (ustekinumab)

Crohn’s Disease H2H vs. HUMIRA (SEAVUE)
*This information is accurate as of July 21, 2021 to the best of the Company's knowledge. Johnson & Johnson assumes no obligation to update this information.
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