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Pharmaceutical Pipeline

Download Report

Selected Pharmaceuticals in Late Stage U.S. and E.U. Development or Registration as of July 21, 2021

Therapeutic Area
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Cardiovascular and Metabolism Immunology Pulmonary Hypertension
20 of 53 Total Indications

Cardiovascular and Metabolism

aprocitentan

Difficult to treat hypertension 2
Phase III US
Phase III EU

XARELTO (rivaroxaban)

Infrainguinal revascularized PAD 3
Filed 10/20 US

XARELTO (rivaroxaban)

Pediatric VTE/CHD (Fontan) 3
Filed 6/21 US

XARELTO (rivaroxaban)

COVID-19 MI (PREVENT-HD) 3
Phase III US

Immunology

nipocalimab​

Warm Autoimmune Hemolytic Anemia
Phase III US
Phase III EU

SIMPONI (golimumab)

Pediatric Ulcerative Colitis
Phase III US
Phase III EU

STELARA (ustekinumab)

Pediatric Crohn's Disease
Phase III US
Phase III EU

STELARA (ustekinumab)

Pediatric Ulcerative Colitis
Phase III US
Phase III EU

TREMFYA (guselkumab)

Crohn's Disease
Phase IIB/III US
Phase IIB/III EU

TREMFYA (guselkumab)

Pediatric Psoriasis
Phase III US
Phase III EU

TREMFYA (guselkumab)

Ulcerative Colitis Monotherapy
Phase IIB/III US
Phase IIB/III EU

TREMFYA (guselkumab)

Psoriatic Arthritis Structural Damage
Phase III US

Pulmonary Hypertension

macitentan

Chronic thromboembolic pulmonary hypertension 75mg
Phase III US
Phase III EU

macitentan

Pulmonary arterial hypertension 75mg
Phase III US
Phase III EU

macitentan w/tadalafil FDC

Pulmonary arterial hypertension
Phase III US
Phase III EU

OPSUMIT (macitentan)

Fontan-palliated in adolescent (>12 years old) and adult patients
Phase III US
Phase III EU

OPSUMIT (macitentan)

Pediatric pulmonary arterial hypertension
Phase III US
Phase III EU

UPTRAVI (selexipag)

Pulmonary arterial hypertension IV
Filed 9/20 US

UPTRAVI (selexipag)

Chronic thromboembolic pulmonary hypertension
Phase III US
Phase III EU

UPTRAVI (selexipag)

Pediatric pulmonary arterial hypertension
Phase III US
Phase III EU
This information is accurate as of the date hereof to the best of the Company's knowledge. Johnson & Johnson assumes no obligation to update this information. (2) aprocitentan developed in collaboration with Idorsia; (3) XARELTO co-developed with Bayer HealthCare; (5) DARZALEX licensed from Genmab A/S; (6) IMBRUVICA developed in collaboration with Pharmacyclics, LLC, an AbbVie company; (7) BALVERSA discovered in collaboration with Astex Pharmaceuticals, Inc.; (8) Niraparib licensed from Tesaro; (9) BCMA CAR-T licensed from Legend Biotech; (10) Monovalent Ebola Vaccine developed in collaboration with Bavarian Nordic A/S, and MVA-BN-Filo® is licensed-in from Bavarian Nordic A/S; (11) DUOBODY platform licensed from Genmab relates to several bispecific antibody programs (Amivantamab, Teclistamab , Talquetamab);
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